A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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Nanotechnology delivers A selection of alternatives to add to biology. Here I'll existing illustrations where by nanofabrication – the ability to make confined structures with Proportions at will – is used to examine the biophysics of single molecules and cells. I'll existing some illustrations from our lab:
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Considering that 2000, Dekker has shifted the main target of his get the job done towards biophysics the place he experiments the Qualities of one biomolecules and cells utilizing the tools of nanotechnology. This variation of subject was pushed by his fascination for the exceptional operating of Organic molecular buildings, as well as through the prolonged-expression standpoint that many intriguing discoveries is often envisioned Within this discipline.[five] Present-day lines of study in his biophysics group are while in the regions of:[six]
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and initial at any time examine of the dynamics DNA supercoils and the invention of supercoil hopping
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes
You're a Christian. If you might make such a artificial cell, would you be just one stage nearer to God, or would the role of God have diminished rather once again?
Movement-driven rotary motors for example windmills and h2o wheels drive functional processes in human society. Despite the fact that samples of these types of rotary motors also feature prominently in cell biology, their synthetic construction in the nanoscale has remained tough. Listed here we display stream-pushed rotary movement of the self-arranged DNA nanostructure that is definitely docked on to a nanopore in a skinny stable-point out membrane. An elastic DNA bundle self-assembles right into a chiral conformation on phoretic docking on to the reliable-condition nanopore, and subsequently shows a sustained unidirectional rotary movement of up to twenty rev s−one.
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Extremely amazing, but that wasn’t definitely in which my desire lay. I wanted to pioneer and I experienced the sensation that was not attainable, as the most fascinating basic insights cees dekker experienced now been uncovered. But my area experienced made numerous interesting new applications to evaluate person molecules. I decided that I planned to utilize this to biology, to look at it from a physical perspective.’
Testing pseudotopological and nontopological versions for SMC-pushed DNA loop extrusion against roadblock-traversal experiments
A lot of new phenomena had been found out, and he and his investigation group recognized a leading posture On this field of investigation. Dekker and his study team found new physics of nanotubes and explored the feasibility of molecular electronics. In 1998, they have been the very first to make a transistor depending on only one nanotube molecule.
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The biophysicist from Delft – who has been one of the most cited experts from the Netherlands For several years – will take his responsibility to add to your clarification and popularisation of his perform in the border of physics and biology extremely very seriously and often appears in the media; Otherwise to speak about his work, then about the connection among science and his Christian faith.